Brazil held on for the victory despite being reduced to ten men at half-time.
Yaya Toure is on the 23-man Ballon d'Or shortlist.
Emmanuel Emenike's retirement shocks Sunday Oliseh.
Reigning champions Nigeria thrashed hosts Chile 5:1 to book their place in the last 16.
'The Golden Eaglets' began the defence of their Fifa Under-17 World Cup crown with a 2:0 victory.
Four nations will represent Africa at the Fifa Under-17 World Cup finals in Chile.
2018 World Cup second round qualifiers.
Delay would "create further instability".
Chad and Comoros with shock wins.
Yaya Toure has been included on an initial list of 37 names.
Round of 32
Match 82
Day 21
Belgium vs Senegal 3:2
Goals Belgium
R. Lukaku (86')
Y. Tielemans (89', 120'+5 pen)
Goals Senegal
H. Diarra (25')
I. Sarr (51')
Belgium
Senegal