African Champions League 2016
2nd round / 1st leg
2015 Champions: TP Mazembe
| 98 | 9 Apr 2016 - 4 p.m. | |
 AS Vita Club |
1 : 0 | mamelodi-sundowns  |
| 99 | 9 Apr 2016 - 4 p.m. | |
 Al Merreikh |
2 : 2 | Entente Setif  |
| 100 | 9 Apr 2016 - 4 p.m. | |
 Wydad Casablanca |
2 : 0 | TP Mazembe |
| 101 | 9 Apr 2016 - 4 p.m. | |
 Enyimba |
3 : 0 | Etoile du Sahel  |
| 102 | 9 Apr 2016 - 4 p.m. | |
 Stade Malien |
1 : 3 | ZESCO United  |
| 103 | 9 Apr 2016 - 4 p.m. | |
 Young Africans |
1 : 1 | Al Ahly SC  |
| 104 | 9 Apr 2016 - 4 p.m. | |
 ASEC Mimosas |
2 : 0 | Al Ahli Tripoli  |
| 105 | 9 Apr 2016 - 4 p.m. | |
| Zamalek |
2 : 0 | Mouloudia Béjaïa |