African Champions League 2015
1st round / 2nd leg
2014 Champions: Entente Setif (Algeria)
| 67 | 5 Apr 2015 - 6 p.m. | |
 AS Kaloum |
1 : 1 | ZESCO United  |
| 68 | 4 Apr 2015 - 6 p.m. | |
 AS Pikine |
1 : 1 | USM Alger  |
| 69 | 5 Apr 2015 - 6 p.m. | |
 Big Bullets |
1 : 1 | Al Hilal  |
| 70 | 5 Apr 2015 - 6 p.m. | |
 SM Sanga Balende |
2 : 0 | Coton Sport  |
| 71 | 5 Apr 2015 - 6 p.m. | |
 Esperance |
3 : 1 | Cosmos de Bafia |
| 72 | 4 Apr 2015 - 6 p.m. | |
 Kabuscorp |
2 : 1 | Al Merreikh |
| 73 | 5 Apr 2015 - 6 p.m. | |
| CS Sfaxien |
1 : 0 | AC Semassi  |
| 74 | 5 Apr 2015 - 6 p.m. | |
 Asante Kotoko |
1 : 2 | MC El Eulma |
| 76 | 5 Apr 2015 - 6 p.m. | |
 AC Leopards |
1 : 0 | Gor Mahia  |
| 78 | 4 Apr 2015 - 6 p.m. | |
 Kano Pillars |
2 : 1 | Moghreb Tétouan  |
| 79 | 4 Apr 2015 - 6 p.m. | |
 Real Banjul |
0 : 2 | Entente Setif |
| 80 | 5 Apr 2015 - 6 p.m. | |
| Raja Casablanca |
2 : 0 | Kaizer Chiefs  |
| 81 | 5 Apr 2015 - 6 p.m. | |
| TP Mazembe |
3 : 1 | mamelodi-sundowns |
| 82 | 4 Apr 2015 - 6 p.m. | |
 Stade Malien |
2 : 1 | AS Mangasport  |
| 83 Alexandria Stadium, Alexandria | 4 Apr 2015 - 5 p.m. | |
 Smouha SC |
2 : 0 | Enyimba |
| 84 Petro Sport Stadium, Cairo | 4 Apr 2015 - 5 p.m. | |
| Al Ahly SC |
2 : 0 | APR  |