African Champions League 2015
1st round / 1st leg
2014 Champions: Entente Setif (Algeria)
| 51 | 15 Mar 2015 - 6 p.m. | |
 ZESCO United |
1 : 1 | AS Kaloum  |
| 52 | 15 Mar 2015 - 6 p.m. | |
 USM Alger |
5 : 1 | AS Pikine  |
| 53 | 15 Mar 2015 - 6 p.m. | |
 Al Hilal |
4 : 0 | Big Bullets  |
| 54 | 15 Mar 2015 - 6 p.m. | |
 Coton Sport |
0 : 0 | SM Sanga Balende  |
| 55 | 15 Mar 2015 - 6 p.m. | |
| Cosmos de Bafia |
0 : 1 | Esperance  |
| 56 | 15 Mar 2015 - 6 p.m. | |
| Al Merreikh |
2 : 0 | Kabuscorp  |
| 57 | 15 Mar 2015 - 6 p.m. | |
 AC Semassi |
0 : 5 | CS Sfaxien |
| 58 | 15 Mar 2015 - 6 p.m. | |
| MC El Eulma |
0 : 0 | Asante Kotoko  |
| 60 | 15 Mar 2015 - 6 p.m. | |
 Gor Mahia |
0 : 1 | AC Leopards  |
| 62 | 15 Mar 2015 - 6 p.m. | |
 Moghreb Tétouan |
4 : 0 | Kano Pillars  |
| 63 | 15 Mar 2015 - 6 p.m. | |
 Real Banjul |
1 : 1 | Entente Setif |
| 64 | 15 Mar 2015 - 6 p.m. | |
 Kaizer Chiefs |
0 : 1 | Raja Casablanca |
| 65 | 15 Mar 2015 - 6 p.m. | |
| mamelodi-sundowns |
1 : 0 | TP Mazembe |
| 66 | 15 Mar 2015 - 6 p.m. | |
 AS Mangasport |
1 : 3 | Stade Malien  |
| 67 | 15 Mar 2015 - 5 p.m. | |
| Enyimba |
1 : 0 | Smouha SC  |
| 68 | 15 Mar 2015 - 5 p.m. | |
 APR |
0 : 2 | Al Ahly SC |