Tunisia beat Egypt and Algeria beat Togo.
Former winners Nigeria, Ivory Coast and Zambia lose at home.
Kessie played for Ivory Coast at the U-17 World Cup in the UAE.
Mohamed Salah scored 15 goals in 31 Serie A games for Roma in 2016-17
Zanzibar was admitted as a full (CAF) member in March.
Saint George beat Vita Club, Ahly win over Wydad.
Holders TP Mazembe draw as Zesco United win at home.
all matches
Uganda's KCCA beat Nigeria's Rivers United.
Beira and Zanaco earn narrow wins
AFRICAN CHAMPIONS LEAGUE 2018
QUARTER-FINALS
Wydad Casablanca vs Entente Setif 0:0
TP Mazembe vs Primeiro de Agosto 1:1
Étoile du Sahel vs Espérance 1:0
Al Ahly vs Horoya 4:0
Algeria
Angola
Egypt
Guinea
Morocco
Tunisia