All four matches so far have been 1:1, meaning lots will be drawn to decide the qualifiers if Wednesday's matches are identical draws.
Max Gradel struck late to earn Ivory Coast a draw with Mali and keep alive their hopes of reaching the Africa Cup of Nations quarter-finals.
Gyan scores late winner on return from malaria
Senegal took top spot in Africa Cup of Nations Group C after coming from behind to hold South Africa.
Cape Verde and DR Congo play out draw.
Tunisia come back to beat wasteful Zambia.
Burkina Faso held by hosts in stalemate
Congo win first Nations Cup match since 1974.
DAY 21
Match 52
Senegal vs Egypt 4:2
FACTS
Senegal wins the Africa Cup 2022 after defeating Egypt in a penalty shootout 4:2. Sadio Mane netted the winning spot-kick as Senegal beat Egypt on penalties to clinch their first-ever Africa Cup of Nations after a 0:0 draw.
Egypt
Senegal